Figure 4.

Alterations in leukocyte trafficking in the BAL fluid and lung tissue in Pla2r1^−/− mice. Concentrations of (A) eosinophils and (B) T cells were increased in Pla2r1^−/− mice in the BAL fluid after OVA, whereas there were no differences in the concentrations of (C) dendritic cells (DCs), (D) polymorphonuclear neutrophils (PMNs), (E) recruited macrophages (Macs), or (F) resident macrophages relative to WT mice exposed to OVA. Although the concentrations of (G) eosinophils and (H) T cells were unchanged, there was an increase in the concentration of (I) DCs in lung tissue from Pla2r1^−/− mice exposed to OVA relative to WT controls. ns, not significant. Data are represented as means ± SEM.