TABLE 2.
Expression of AlgU regulon genes in PAKmucA22
| Group and ID no. | Name | Function | Fold change in mucA22 vs wild type |
|---|---|---|---|
| Alginate biosynthesis genes | |||
| PA3540 | algD | Alginate biosynthesis | 64.2 |
| PA3541 | alg8 | Alginate biosynthesis | 29.9 |
| PA3542 | alg44 | Alginate biosynthesis | 28.9 |
| PA3543 | algK | Alginate biosynthesis | 81.2 |
| PA3544 | algE | Alginate biosynthesis | 47.9 |
| PA3545 | algG | Alginate biosynthesis | 38.0 |
| PA3546 | algX | Alginate biosynthesis | 86.0 |
| PA3547 | algL | Alginate biosynthesis | 43.7 |
| PA3548 | algI | Alginate biosynthesis | 55.2 |
| PA3549 | algJ | Alginate biosynthesis | 27.2 |
| PA3550 | algF | Alginate biosynthesis | 70.5 |
| PA3551 | algA | Phosphomannose isomerase | 38.7 |
| Alginate biosynthesis regulatory genes | |||
| PA0762 | algU | Sigma factor | 2.6 |
| PA0763 | mucA | Anti-sigma factor | 2.4 |
| PA0764 | mucB | Negative regulator for alginate biosynthesis | 1.3 |
| PA5261 | algR | Alginate biosynthesis; two-component system | 1.5 |
| PA5483 | algB | Alginate biosynthesis; two-component system | 2.0 |
| PA5484 | kinB | Two-component sensor | 2.1 |
| Genes known to be up regulated in mucA mutant | |||
| PA0059 | osmC | Osmotically inducible protein | 3.8 |
| PA0376 | rpoH | Sigma factor | 1.3 |
| PA4876 | osmE | Osmotically inducible lipoprotein | 3.0 |
| PA5489 | dsbA | Thiol:disulfide interchange protein | 1.3 |