Table 1.

Summary of Bioinformatics Analyses of Top-Ranking SNPs on the Human MYLK Gene

Chromosome	Position	SNP ID	Reference Allele	Alternate Allele	Frequency	dPSI	SpliceScan Change	Predicted Outcome
3	123451738	rs147245669	C	T	0.0005	−58.9	Donor = 0.01 Exon 11 score = 0	Increased MLCK 2; more skipping
3	123451743	rs77323602	T	C	0.01	5.44	Donor = 0.92 Exon 11 score = 0.15	Increased MLCK1; more inclusion

Definition of abbreviations: C, cytosine; dPSI, change in percent of transcripts with the exon spliced in; MLCK, myosin light-chain kinase; SNP, single-nucleotide polymorphism; T, thymine.