Table 4.
Outcomes summary for all patients shocked at different energy levels (per energy level analysis)
| Energy delivered | Number of patients | Number of ROSC after the shock (%) | Duration of collapse prior to first shock (minutes)a
|
Duration of VF/pulseless VT prior to first shock at the energy level (minutes)b
|
24-hour survival (%)d | 7-day survival (%)d | 30-day survival (%)d | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROSC no, mean (SD) | ROSC yes, mean (SD) | 95% CI of difference (P-valuec) | ROSC no, mean (SD) | ROSC yes, mean (SD) | 95% CI of difference (P-valuec) | ||||||
| First shock at 150 J | 118 | 35 (29.66) | 30.01 (18.75) | 10.57 (15.51) | 12.27–26.61 (P<0.01) | 2.84 (3.51) | 1.06 (1.33) | 0.88–2.68 (P<0.01) | 30 (85.71) | 26 (74.29) | 22 (62.86) |
| First shock at 200 J | 117 | 30 (25.64) | 25.95 (20.18) | 12.63 (15.34) | 5.30–21.34 (P<0.01) | 2.94 (2.57) | 1.73 (1.41) | 0.41–1.96 (P<0.01) | 21 (70.00) | 15 (50.00) | 14 (46.67) |
| Total patients shocked at 150 J | 118 | 48 (40.68) | 32.27 (18.75) | 12.32 (15.16) | 13.40–26.50 (P<0.01) | 3.13 (3.71) | 1.09 (1.27) | 1.08–3.02 (P<0.01) | 37 (77.08) | 33 (68.75) | 29 (60.42) |
| Total patients shocked at 200 J | 165 | 33 (20.00) | 27.74 (19.31) | 13.94 (16.13) | 6.59–21.01 (P<0.01) | 3.16 (3.31) | 1.64 (1.41) | 0.77–2.27 (P<0.01) | 21 (63.64) | 15 (45.45) | 14 (42.42) |
| Total patients shocked at 300 J | 118 | 11 (9.32) | 26.74 (19.15) | 30.73 (19.58) | −16.00–8.06 (P=0.51) | 3.22 (3.47) | 1.64 (1.03) | 0.66–2.51 (P<0.01) | 2 (18.18) | 2 (18.18) | 2 (18.18) |
| Total patients shocked at 360 J | 95 | 37 (38. 95) | 29.29 (15.40) | 18.30 (16.65) | 4.29–17.68 (P<0.01) | 4.18 (4.24) | 1.89 (1.61) | 1.04–3.53 (P<0.01) | 20 (54.05) | 16 (43.24) | 13 (35.14) |
Notes:
a
The duration of collapse prior to first shock is the time duration from collapse to the first shock.
b
The duration of VF/pulseless VT is the duration from onset of VF/pulseless VT to the first shock.
c
The P-value is from (two-sided) two-sample t-test.
d
The denominator of the survival outcome percentage is the number of ROSC patients.
Abbreviations: CI, confidence interval; ROSC, return of spontaneous circulation; SD, standard deviation; VF, ventricular fibrillation; VT, ventricular tachycardia.