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Study summary.
| Displacing agents | Radioligands |
||
|---|---|---|---|
| 18F-FP-(+)-DTBZ | 18F-FP-(−)-DTBZ | ||
| Displacement study | saline (control) | Baboons A, B, and C | Baboon D |
| FP-(+)-DTBZ | Baboons A (0.25 mg/kg) and B (0.5 mg/kg) | Baboon D (0.5 mg/kg) | |
| FP-(−)-DTBZ | Baboon C (0.5 mg/kg) | Baboon D (0.5 mg/kg) | |
| fluvoxamine | Baboons B and C (3 mg/kg) | ||
| Tissue radiometabolite measurement | Baboons C and E | Baboon F | |
