Figure 1.

Cross-sectional correlation of serum miR-122 levels with lipid subspecies (A) and selected proteins related to lipid metabolism (B) in the Bruneck Study. In A, lipid species are arranged by lipid class in eight panels according to the number of total carbon atoms and number of double bonds. Lipid species highlighted with a yellow halo showed statistically significant correlations after Bonferroni correction. For better visibility, those lipid species with alkyl ether linkage are shifted upwards, whereas their alkyl ether–free counterparts are shifted downward. In B, P values significant after Bonferroni correction are shown in bold. The full panel of proteins is shown in Supplementary Fig. 2. AFAM, afamin; CE, cholesteryl ester; CFAH, complement factor H; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PS, phosphatidylserine; SM, sphingomyelin; TAG, triacylglycerol; ZA2G, zinc-α-2-glycoprotein.