Table 4.
Transcription factor genes differentially expressed in ISIAH and WAG renal medulla
| Gene symbol | NCBI gene ID | Gene name | log2 fold_change ISIAH/WAG |
|---|---|---|---|
| Alx1 | 25401 | ALX homeobox 1 | −1.13 |
| Arntl | 29657 | aryl hydrocarbon receptor nuclear translocator-like | −1.01 |
| Bcl6 | 303836 | B-cell CLL/lymphoma 6 | −2.02 |
| Bcl6b | 360551 | B-cell CLL/lymphoma 6, member B | −0.80 |
| Bhlhe22 | 365748 | basic helix-loop-helix family, member e22 | −1.08 |
| Bnc2 | 298189 | basonuclin 2 | 0.61 |
| Btbd11 | 314675 | BTB (POZ) domain containing 11 | −0.65 |
| Ccrn4l | 310395 | CCR4 carbon catabolite repression 4-like (S, cerevisiae) | 0.64 |
| Cebpd | 25695 | CCAAT/enhancer binding protein (C/EBP), delta | −0.83 |
| Dab2 | 79128 | disabled 2, mitogen-responsive phosphoprotein | 0.49 |
| Dmrt2 | 309430 | doublesex and mab-3 related transcription factor 2 | −0.55 |
| Esrrb | 299210 | estrogen-related receptor beta | −0.58 |
| Etv5 | 303828 | ets variant 5 | −0.70 |
| Fhl1 | 25177 | four and a half LIM domains 1 | 1.09 |
| Gcfc2 | 312474 | GC-rich sequence DNA-binding factor 2 | −0.61 |
| Gne | 114711 | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | −0.51 |
| Grhl1 | 313993 | grainyhead-like 1 (Drosophila) | 1.91 |
| Hand2 | 64637 | heart and neural crest derivatives expressed 2 | expression was detected only in ISIAH rats |
| Hes6 | 316626 | hes family bHLH transcription factor 6 | −0.72 |
| Id3 | 25585 | inhibitor of DNA binding 3 | −0.50 |
| Id4 | 291023 | inhibitor of DNA binding 4 | 0.47 |
| Ilf2 | 310612 | interleukin enhancer binding factor 2 | −0.46 |
| Irf7 | 293624 | interferon regulatory factor 7 | 0.59 |
| Irf8 | 292060 | interferon regulatory factor 8 | −0.58 |
| Khdrbs3 | 64015 | KH domain containing, RNA binding, signal transduction associated 3 | −1.23 |
| Lmo2 | 362176 | LIM domain only 2 | −0.79 |
| Map2 | 25595 | microtubule-associated protein 2 | −1.44 |
| Mcm7 | 288532 | minichromosome maintenance complex component 7 | 0.61 |
| Mef2c | 499497 | myocyte enhancer factor 2C | −0.59 |
| Mybl1 | 297783 | myeloblastosis oncogene-like 1 | −0.56 |
| Nfkbil1 | 361794 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 0.98 |
| Notch3 | 56761 | notch 3 | −0.50 |
| Npas2 | 316351 | neuronal PAS domain protein 2 | −0.90 |
| Nr2f1 | 81808 | nuclear receptor subfamily 2, group F, member 1 | −1.31 |
| Nrip3 | 361625 | nuclear receptor interacting protein 3 | −0.83 |
| Osr1 | 298878 | odd-skipped related transciption factor 1 | −1.29 |
| Osr2 | 315039 | odd-skipped related transciption factor 2 | 1.17 |
| P8 | 113900 | nuclear proten 1 | −0.95 |
| Patz1 | 305471 | POZ (BTB) and AT hook containing zinc finger 1 | 0.57 |
| Paxbp1 | 681004 | PAX3 and PAX7 binding protein 1 | −0.53 |
| Pou2af1 | 690528 | POU class 2 associating factor 1 | 1.19 |
| Prdm6 | 307305 | PR domain containing 6 | 1.50 |
| Prox1 | 305066 | prospero homeobox 1 | −1.06 |
| Sim1 | 309888 | single-minded family bHLH transcription factor 1 | −0.50 |
| Smarcd3 | 296732 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | −0.58 |
| Spry4 | 291610 | sprouty homolog 4 (Drosophila) | −0.61 |
| Stat5a | 24918 | signal transducer and activator of transcription 5A | 0.63 |
| Tcerg1l | 361669 | transcription elongation regulator 1-like | 4.09 |
| Tcf21 | 252856 | transcription factor 21 | −0.48 |
| Tcf4 | 84382 | transcription factor 4 | −0.66 |
| Tle2 | 299636 | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | −0.61 |
| Zbtb16 | 353227 | zinc finger and BTB domain containing 16 | −1.11 |
| Zdhhc2 | 246326 | zinc finger, DHHC-type containing 2 | 0.75 |
| Zfhx2 | 305888 | zinc finger homeobox 2 | −0.88 |
| Zfp189 | 313219 | zinc finger protein 189 | −0.62 |
| Zfp354a | 24522 | zinc finger protein 354A | 0.58 |
| Zfp449 | 684901 | zinc finger protein 449 | −0.71 |
| Zfp710 | 293044 | zinc finger protein 710 | −0.76 |
| Zfp958 | 100302405 | zinc finger protein 958 | −0.64 |
ISIAH and WAG – rat strains used in the study