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. 2016 Dec 28;17(Suppl 14):1046. doi: 10.1186/s12864-016-3356-0

Table 3.

Cox regression calculation results for Drosophila after exposure to different stress factors

Genotype Factor Parameter Stresses
Paraquat CuSO4 CdCl2 NaCl
Appl-GAL4 > UAS-Gclc Sex HR 1.026 0.5152 0.4533 0.4533
95% CI 0.9546-1.102 0.4783-0.555 0.4201-0.4891 0.4201-0.4891
UAS-Gclc Age HR 1.078 1.0681 1.0654 1.0824
95% CI 1.0757-1.0802 1.0661-1.0701 1.0634-1.0674 1.0800-1.0848
Sex HR 1.5808 0.5105 0.4301 0.769
95% CI 1.4650-1.7057 0.4724-0.5516 0.3975-0.4655 0.7128-0.8297
Sex_male:
Appl-GAL4 > UAS-Gclc
HR 0.5333 0.7105 95 0.5943 0.7561
95% CI 0.4947-0.5749 0.6597-0.7651 0.5513-0.6407 0.7015-0.8150
Sex_female:
Appl-GAL4 > UAS-Gclc
HR 0.3558 0.3914 0.4064 0.3727
95% CI 0.3296-0.3841 0.3625-0.4226 0.3769-0.4383 0.3451-0.4025

The first column shows the genotype compared flies in the analysis of the impact of these factors in the second column. HR - hazard ratio (the predicted risk of change when the value of the independent variable on the unit); 95% CI - a 95% confidence interval; Sex - a series of data showing the hazard regression for the flies with a certain genotype under the influence of each of the stress when factor is the individual’s sex; Age - a series of data showing the hazard regression for the flies with a certain genotype under the influence of each of the stress when factor is the individual’s age; Sex_male: Appl-GAL4 > UAS-Gclc a series of data showing the hazard ratio for flies with UAS-Gclc and Appl-GAL4 > UAS-Gclc genotypes when exposed to each of stresses, with the assessment of the impact of interacting factors (male sex, and genotype Appl-GAL4 > UAS-Gclc); Sex_female: Appl-GAL4 > UAS-Gclc a series of data showing the hazard ratio for flies with UAS-Gclc and Appl-GAL4 > UAS-Gclc genotypes when exposed to each of stresses, with the assessment of the impact of interacting factors (female sex, and genotype Appl-GAL4 > UAS-Gclc)

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