Table 3.
Cox regression calculation results for Drosophila after exposure to different stress factors
Genotype | Factor | Parameter | Stresses | |||
---|---|---|---|---|---|---|
Paraquat | CuSO4 | CdCl2 | NaCl | |||
Appl-GAL4 > UAS-Gclc | Sex | HR | 1.026 | 0.5152 | 0.4533 | 0.4533 |
95% CI | 0.9546-1.102 | 0.4783-0.555 | 0.4201-0.4891 | 0.4201-0.4891 | ||
UAS-Gclc | Age | HR | 1.078 | 1.0681 | 1.0654 | 1.0824 |
95% CI | 1.0757-1.0802 | 1.0661-1.0701 | 1.0634-1.0674 | 1.0800-1.0848 | ||
Sex | HR | 1.5808 | 0.5105 | 0.4301 | 0.769 | |
95% CI | 1.4650-1.7057 | 0.4724-0.5516 | 0.3975-0.4655 | 0.7128-0.8297 | ||
Sex_male: Appl-GAL4 > UAS-Gclc |
HR | 0.5333 | 0.7105 95 | 0.5943 | 0.7561 | |
95% CI | 0.4947-0.5749 | 0.6597-0.7651 | 0.5513-0.6407 | 0.7015-0.8150 | ||
Sex_female: Appl-GAL4 > UAS-Gclc |
HR | 0.3558 | 0.3914 | 0.4064 | 0.3727 | |
95% CI | 0.3296-0.3841 | 0.3625-0.4226 | 0.3769-0.4383 | 0.3451-0.4025 |
The first column shows the genotype compared flies in the analysis of the impact of these factors in the second column. HR - hazard ratio (the predicted risk of change when the value of the independent variable on the unit); 95% CI - a 95% confidence interval; Sex - a series of data showing the hazard regression for the flies with a certain genotype under the influence of each of the stress when factor is the individual’s sex; Age - a series of data showing the hazard regression for the flies with a certain genotype under the influence of each of the stress when factor is the individual’s age; Sex_male: Appl-GAL4 > UAS-Gclc a series of data showing the hazard ratio for flies with UAS-Gclc and Appl-GAL4 > UAS-Gclc genotypes when exposed to each of stresses, with the assessment of the impact of interacting factors (male sex, and genotype Appl-GAL4 > UAS-Gclc); Sex_female: Appl-GAL4 > UAS-Gclc a series of data showing the hazard ratio for flies with UAS-Gclc and Appl-GAL4 > UAS-Gclc genotypes when exposed to each of stresses, with the assessment of the impact of interacting factors (female sex, and genotype Appl-GAL4 > UAS-Gclc)