. 2017 Jan 20;12(1):e0169716. doi: 10.1371/journal.pone.0169716

Table 3. Plasmatic Calcium, Phosphorous, Magnesium, CK and T4 concentrations in the different populations.

	Healthy-early lactation	DCS-early lactation	DCS—late lactation	DCS—dry period
Calcium (mmol/L)	2.24 ± 0.21	1.57 ± 0.76^a	2.06 ± 0.56^b	2.19 ± 0.83^c
Calcium (mmol/L)	1.72–2.25–2.52	0.50–1.54–2.92	0.90–2.09–2.73	0.87–2.22–4.21
Phosphorus (mmol/L)	1.74 ± 0.32	1.21 ± 0.89^a	1.67 ± 0.93^b	1.97 ± 1.01^c
Phosphorus (mmol/L)	1.04–1.77–2.29	0.17–1.03–3.51	0.21–1.66–3.18	0.35–1.80–4.10
Magnesium (mmol/L)	0.87 ± 0.12	1.16 ± 0.55^a	1.00 ± 0.52^b	1.06 ± 0.47
Magnesium (mmol/L)	0.62–0.89–1.08	0.30–1.10–2.22	0.16–1.00–1.86	0.23–1.04–1.90
CK (UI/L)	120 ± 50	1466 ± 2069^a	1446 ± 1209	1807 ± 1269
CK (UI/L)	62-106-241	82-772-4672	105-1102-3863	60-2141-3000
T4 (nmol/L)	34 ± 11	27 ± 13^a	35 ± 13^b	22 ± 14^c
T4 (nmol/L)	17-33-58	7-24-58	6-31-80	7-17-52

Data represented as mean ± standard deviation and as 2.5–50–97.5 percentiles.

DCS–downer cow syndrome; CK = creatine kinase; T4 = thyroxine;

^a = significantly different from healthy cows;

^b = significantly different from DCS cows in the early lactation period;

^c = significantly different from DCS cows in early and late lactation.