Table 1. Number of SNPs and indel mutations identified through the WES analysis and candidate selection.
SNP filtering step | Number of SNPs | Indel filtering step | Number of indels |
---|---|---|---|
Total SNPs | 173,849 | Total indels | 17,851 |
Coverage ≥10x SNPs | 122,652 | Coverage ≥ 10x indels | 14,030 |
Gene coding SNPs | 97,734 | Mutated in all NAD and NAD-parents | 2,124 |
Exon coding SNPs | 46,639 | NAD homozygous indels | 135 |
NAD homozygous and NAD-parent heterozygous SNPs | 59 | NAD-parent heterozygous indels | 5 |
Control wild-type or heterozygous SNPs | 18 | Control wild-type or heterozygous indels | 2 |
Missense mutations | 10 | Exon coding indels | 0 |