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. 2017 Jan 20;12(1):e0170073. doi: 10.1371/journal.pone.0170073

Table 5. Area under the ROC curve and summary statistics of the diagnostic value of the LSM and AFC indices for stages of liver fibrosis ≥ F2.

LSM AFC
AUROC 0.709** 0.866***
Significance (2-tailed) 0.006 0.000
Cut-off value 7.042 2.256
Youden index 0.426 0.648
Sensitivity 72.22% 83.33%
Specificity 70.37% 81.48%
PPV 35.14% 50.00%
NPV 91.94% 95.65%
Diagnose accuracy 70.71% 81.82%

** the significance level of the statistics P < 0.01.

*** the significance level of the statistics P < 0.001.