Table 4. Studies of the association of ocular biometry with retinal vascular caliber.
| Study reference | Study, number of gradable images | Ethnicity, n (%) | Ocular Biometric Parameter | Mean age (sd), range | Effect on CRAE (per 1 mm increase in each parameter) | Effect on CRVE (per 1 mm increase in each parameter) |
|---|---|---|---|---|---|---|
| Current study, 2016 | 86 | Malay: 86 (100%) | Axial length | 9.44 (1.75) years, 6 to 12 years | β = -4.25 (p = 0.03) | β = -3.44 (p = 0.16) |
| Corneal curvature | β = 1.09 (p = 0.23) | β = 1.11 (p = 0.33) | ||||
| Anterior chamber depth | β = -10.54 (p = 0.13) | β = -2.46 (p = 0.78) | ||||
| Gopinath et al,2013 [29] | SPEDS, 5287 | Caucasian: 3241 (61.3%); East Asian: 831 (15.7%); Southeast Asian: 272 (5.2%); Middle Eastern: 324 (6.1%); Others: 619 (11.7%) | Axial length | 36 to <72 months | β = 3.67 (p = 0.005) | β = -6.53 (p < 0.001) |
| 6 years old | β = -5.30 (p < 0.001) | β = 7.12 (p = 0.01) | ||||
| 12 years (n | β = -3.96 (p < 0.001) | β = -6.72 (p < 0.001) | ||||
| 16–17 years | β = -4.03 (p < 0.001) | β = -6.85 (p < 0.001) | ||||
| Corneal curvature | 36 to <72 months | β = -14.53 (p < 0.001) | β = -14.29 (p = 0.004) | |||
| 6 years old | β = -10.08 (p < 0.001) | β = -14.36 (p < 0.001) | ||||
| 12 years | β = -9.32 (p < 0.001) | β = -12.92 (p < 0.001) | ||||
| 16–17 years | β = -6.77 (p < 0.001) | β = -11.84 (p < 0.001) | ||||
| Li et al, 2011 [30] | STARS, 469 | Chinese: 469 (100%) | Axial length | 60.68 (7.3) months | β = -3.52 (p = 0.023) | β = -5.55 (p = 0.008) |
| Corneal curvature | β = -5.85 (p = 0.093) | β = -13.79 (p = 0.004) | ||||
| Anterior chamber depth | β = 4.76 (p = 0.202) | β = 3.55 (p = 0.898) | ||||
| Cheung et al., 2007 [31] | SCORM, 767 | Chinese: 654 (85.3%); Malay: 75 (9.8%); Others: 38 (4.9%) | Axial length | 7.8 (0.78) years, 7 to 9 years | β = 0.44 (p = 0.31) | Β = 0.70 (p = 0.25) |
SCORM; Singapore Cohort Study of the Risk Factors for Myopia; STARS, Strabismus, Amblyopia, and Refractive Error Study in Singaporean Chinese Pre-schoolers; SPEDS, Sydney Paediatric Eye Disease Study.