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Increased susceptibility of PERK−/− MEFs to VSV infection. PERK+/+ and PERK−/− MEFs were left untreated (A) or treated with mouse IFN-α/β (1,000 IU/ml) (B) for 18 h in the absence (A and B, left panels) or presence (A and B, right panels) of VSV infection at an MOI of 1. Cells were photographed at ×100 magnification at indicated times postinfection.
