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Augmentation of TGF-β-mediated effects by FAST-1 and Smad2. MCF-7 cells (A) and monocyte-derived macrophages (B) were transfected with pGL-HIV-1-LTR along with pcDNA3.1 or expression vector of the indicated factor and either untreated or treated with TGF-β (200 pg/ml). Results are shown as luciferase activity relative to that of pGL-HIV-1-LTR and pcDNA3.1 when untreated. Error bars represent standard deviations from triplicate experiments.
