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ZAP does not target AREs. pGL3-Luc reporters containing different types of AREs were cotransfected into 293A cells with an empty vector or a vector expressing TTP or ZAP. At 48 h posttransfection, the cells were lysed and the luciferase activities were measured. The luciferase activity in cells transfected with the pGL3-Luc reporters was arbitrarily defined as 100. The data are means plus SD of three independent experiments.
