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. 2004 Dec;78(23):13082–13089. doi: 10.1128/JVI.78.23.13082-13089.2004

FIG. 6.

FIG. 6.

Cytotoxic T lymphocytes generated in the absence of regulatory T cells efficiently lyse peptide-sensitized targets. Splenocytes were isolated and expanded in vitro for 5 days, and CTL activity was determined as described in Materials and Methods. (A and B) CTL activity measured during the acute phase of immunization for gB-DNA and SS-CpG1826, respectively. (C and D) Memory-phase CTL activity for gB-DNA and SS-CpG1826, respectively.