TABLE 1.
Mean titers of virus in the ovaries collected at days 3, 5, and 7 following challenge with 105 PFU/mouse of vaccinia virus gB
| Group | Mean log10 titer ± SDa
|
||
|---|---|---|---|
| Day 3 | Day 5 | Day 7 | |
| HSV + PC61 | 0 | 0 | 0 |
| HSV + isotype Ig | 1.28 ± 0.31 | 0 | 0 |
| Phosphate-buffered saline | 3.08 ± 1.1 | 4.4 ± 0.19 | 3.73 ± 0.19 |
| SS-CpG1826 + PC61 | 1.21 ± 0.40 | 1.11 ± 0.93 | 1.0 ± 0.67 |
| SS-CpG1826 + isotype Ig | 1.92 ± 0.14 | 1.01 ± 0.5 | 1.1 ± 0.41 |
| SS-CpG2138 + PC61 | 4.81 ± 1.3 | 4.01 ± 0.29 | 3.37 ± 0.39 |
| gB-DNA + PC61 | 1.28 ± 0.62 | 0 | 0 |
| gB-DNA + isotype Ig | 3.00 ± 1.78 | 2.51 ± 0.2 | 0 |
| β-Galactosidase DNA | 4.5 ± 0.1 | 4.54 ± 0.68 | 3.98 ± 0.67 |
a
Values represent means for four mice per group in two separate experiments.