TABLE 2.
Mean titers of virus in the ovaries collected at days 3, 5, and 7 following challenge with 107 PFU/mouse of vaccinia virus gB
| Group | Mean log10 titer ± SDa
|
||
|---|---|---|---|
| Day 3 | Day 5 | Day 7 | |
| HSV + PC61 | 1.12 ± 0.16 | 0 | 0 |
| HSV + isotype Ig | 2.79 ± 0.21 | 1.10 ± 0.12 | 0 |
| Phosphate buffered saline | 4.11 ± 1.5 | 5.56 ± 0.9 | 3.23 ± 0.32 |
| SS-CpG1826 + PC61 | 4.12 ± 0.16 | 4.0 ± 1.01 | 2.15 ± 0.78 |
| SS-CpG1826 + isotype Ig | 4.790 ± 0.29 | 4.10 ± 0.24 | 2.29 ± 0.65 |
| SS-CpG2138 + PC61 | 4.11 ± 1.5 | 5.56 ± 0.9 | 3.23 ± 0.32 |
| gB-DNA PC61 | 1.21 ± 0.65 | 1.1 ± 0.43 | 0 |
| gB-DNA + isotype Ig | 3.99 ± 1.18 | 3.21 ± 0.23 | 2.31 ± 0.21 |
| β-Galactosidase DNA + PC61 | 4.9 ± 0.13 | 5.3 ± 1.89 | 4.18 ± 0.77 |
a
Values are means for four mice per group in two separate experiments..