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Effect of alpha/beta interferon neutralization on viral yield. Macrophages were infected with the four viral strains. After washing the inoculum, the medium was replaced with 400 μl of medium containing the indicated dilutions of neutralizing anti-alpha/beta interferon antibody. The medium was harvested 24 h p.i., and the infectivity was measured by plaque assay. Each point represents the mean and standard error of the mean of five individual samples from two independent experiments.
