TABLE 3.
Sequence identity of catalytic region of I7L among various poxviruses
| Virus | Family | Catalytic triad sequence | % Identity with vvI7L ORF | P4b (AGA) |
|---|---|---|---|---|
| VV I7L | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321-NQLLESECGM | 100 | Yes |
| Cowpox | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 96 | Yes |
| Camelpox | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 99 | Yes |
| Variola major | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 99 | Yes |
| Variola minor | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 99 | Yes |
| Monkeypox | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 99 | Yes |
| Ectromelia | Orthopoxvirus | 241- HWKCVIYDKK QCLVSFYDSG 321- NQLLESECGM | 95 | Yes |
| Sheeppox | Capripoxvirus | 251- HWKCVIFDKE KLVVCFYDSG 332- NQLLESECGM | 63 | Yes |
| Lumpy skin | Capripoxvirus | 251- HWKCVIFDKE KLVVCFYDSG 332- NQLLESECGM | 66 | Yes |
| Yaba-like | Yatapoxvirus | 246- HWKCVIINKE KLFVAFYDSG 327- NQLLESECGM | 69 | Yes |
| Swinepox | Suipoxvirus | 249- HWKCVIFDKE HHIVCFYDSG 330- NQLLESECGM | 68 | Yes |
| Rabbit fibroma | Leporipoxvirus | 245- HWKCVIFDKE KQIACFYDSG 321- NQLLESECGM | 66 | AGV |
| Myxoma virus | Leporipoxvirus | 245- HWKCVIFDKE KQIVCFYDSG 326- NQLLESECGM | 66 | AGV |
| Molluscum contagiosum | Molluscipox | 242- HWKSLVFDRR QRLVAFYDSG 322- NQLLESECGM | 62 | Yes |
| Fowlpox virus | Avipoxvirus | 242- HWKCAIYDKN RDFICFYDSG 322- NQLLESECGM | 58 | Yes |
| Canarypox virus | Avipoxvirus | 242- HWKCLIYDRE NDFVCFYDSG 323- NQLMESECGM | 55 | NPa |
| Amsacta moorei | Entomopoxvirus | 254- HFTSAVIDKK RKICYLFNSS 336- IQYDSPDCGM | 25 | NP |
a
NP, not published.