Table 2.
Number of Strongyloides fülleborni eggs per gram of feces in captive olive baboons (Papio anubis) before and after combined treatment with ivermectin and fenbendazole
Baboon |
||||||
A1 | A2 | B1 | B2 | C1 | C2 (control) | |
Before treatment | ||||||
no. of samples | 4 | 7 | 6 | 7 | 5 | 2 |
mean ± SE | 45.1 ± 39.6 | 8.6 ± 2.6 | 4.1 ± 0.9 | 15.8 ± 5.7 | 0.08 ± 0.08 | 26.2 ± 5.2 |
95% CI | −32.5 to 122.7 | 3.6 to 13.6 | 2.4 to 5.8 | 4.7 to 26.9 | −0.08 to 0.2 | 15.9to 36.5 |
median | 8.2 | 7.6 | 4.7 | 14.2 | 0 | 26.2 |
range | 0.4–163.5 | 0.2–17.2 | 0.4–6.0 | 0.2–35.8 | 0.0–0.4 | 21.0–31.5 |
After treatment | ||||||
no. of samples | 15 | 15 | 11 | 11 | 14 | 16 |
mean ± SE | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 5.5 ± 2.2 |
95% CI | 0.0–0.2 | 0.0–0.2 | 0.0–0.3 | 0.0–0.3 | 0.0–0.2 | 1.2–9.8 |
median | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.6 |
range | 0.0–0.0 | 0.0–0.0 | 0.0–0.0 | 0.0–0.0 | 0.0–0.0 | 0.5–28.8 |
% Reduction in parasite load | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 79% |
Mann–Whitney U statistics | T = 111.0 P < 0.001 | T = 133.0 P < 0.001 | T = 87.0 P < 0.001 | T = 105.0 P < 0.001 | T = 77.0 P < 0.033 | T = 33.0 P = 0.058 |
Fecal egg counts after treatment differed significantly (P ≤ 0.05) from that before treatment in all baboons except the control animal.