Table 3.
Number of Trichuris trichiura eggs per gram of feces in captive olive baboons (Papio anubis) before and after combined treatment with ivermectin and fenbendazole
| Baboon |
|||||
| A1 | B1 | B2 | C1 | C2 (control) | |
| Before treatment | |||||
| no. of samples | 2 | 2 | 2 | 2 | 2 |
| mean ± SE | 114.4 ± 89.3 | 15.3 ± 2.0 | 23.2 ± 8.4 | 20.4 ± 3.2 | 32.7 ± 26.1 |
| 95% CI | −60.5 to 289.3 | 11.4 to 19.2 | 6.8–39.8 | 14.0–23.6 | −18.4–83.8 |
| median | 114.4 | 15.3 | 23.2 | 20.3 | 32.7 |
| range | 25.1 to 203.6 | 13.3 to 17.2 | 14.9 to 31.7 | 17.2 to 23.6 | 6.6 to 58.8 |
| After treatment | |||||
| no. of samples | 16 | 12 | 11 | 15 | 16 |
| mean ± SE | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 64.4 ± 15.4 |
| 95% CI | 0.0–0.2 | 0.0–0.2 | 0.0–0.3 | 0.0–0.2 | 34.3–94.5 |
| median | 0.0 | 0.0 | 0.0 | 0.0 | 48.1 |
| range | 0.0–0.0 | 0.0–0.0 | 0.0–0.0 | 0.0–0.0 | 0.8–191.4 |
| % Reduction in parasite load | 100 | 100 | 100 | 100 | −96.9 |
| Mann–Whitney U statistic | T = 33.0 P < 0.001 | T = 25.0 P < 0.001 | T = 25.0 P < 0.001 | T = 31.0 P < 0.001 | T = 15.0 P = 0.623 |
Baboon A2 was not infected with Trichuris trichiura and therefore is not reported here.
Fecal egg counts after treatment differed significantly (P ≤ 0.05) from that before treatment in all baboons except the control animal.