Skip to main content

View full-text article in PMC

. 2017 Jan;56(1):69–78.

Table 3.

Total AUC (mean ± 1 SD) above baseline until nose down for various cardiovascular parameters (heart rate [HR], bpm; blood pressure [BP], mm Hg)

	15% CO₂	30% CO₂	50% CO₂	100% CO₂	Isoflurane	Pentobarbital–phenytoin	P
Total HR^a	6079 ± 3746^c	4075 ± 2342^c	1835 ± 843^b,c	2078 ± 964^b,c	6365 ± 1834^c	16,787 ± 6607^b	<0.0001
HR/s	57.7 ± 34.5^b,c	57.5 ± 32.4^b,c	40.0 ± 15.5^b,c	63.6 ± 25.4^c	104.1 ± 27.2^c	168.1 ± 51.5^b	<0.0001
Total SBP^a	1520 ± 955	1377 ± 716	1003 ± 438	744 ± 216	744 ± 596	423 ± 396	0.0148
SBP/s	13.4 ± 9.7	20.6 ± 10.1^c	25.3 ± 12.0^b,c	23.7 ± 7.2^c	11.8 ± 8.8	4.5 ± 4.3	<0.0001
Total DBP^a	1437 ± 907	1320 ± 732	1008 ± 559	717 ± 268	636 ± 448	519 ± 573	0.0316
DBP/s^a	13.6 ± 8.3	18.4 ± 11.0^c	23.0 ± 11.0^c	21.8 ± 7.5^c	10.2 ± 6.5	5.7 ± 6.3	0.0021
Total MBP^a	1466 ± 921	1350 ± 689	1007 ± 522	719 ± 235	712 ± 525	480 ± 485	0.0375
MBP/s^a	13.9 ± 8.5	19.3 ± 10.2	23.2 ± 11.1^c	22.2 ± 7.0^c	11.4 ± 7.8	5.2 ± 5.3	<0.001

DBP, diastolic blood pressure; HR, heart rate; MBP, mean blood pressure; SBP, systolic blood pressure

CO₂ data have been published previously.²

^a

Data were transformed for analysis.

^b

Value significantly different from that for isoflurane.

^c

Value significantly different from that for pentobarbital–phenytoin.