Table 5.
Peak (mean ± 1 SD) cardiovascular (heart rate [HR], bpm; blood pressure [BP], mm Hg) and activity values
| 15% | 30% | 50% | 100% | Isoflurane | Pentobarbital–phenytoin | P | |
| HR | 678 ± 71.5b | 661 ± 43.2b | 640 ± 39.5b | 709 ± 93.7 | 708 ± 75.8 | 772 ± 45.6 | <0.0001 |
| SBP | 140.3 ± 14.2 | 150.6 ± 15.3 | 145.5 ± 12.8 | 151.7 ± 6.3 | 141.9 ± 11.9 | 134.4 ± 20.5 | 0.0360 |
| DBP | 116.1 ± 10.5 | 117.5 ± 10.0 | 115.4 ± 7.8 | 115.6 ± 4.0 | 109.4 ± 8.4 | 108.6 ± 22.2 | 0.3462 |
| MBP | 125.7 ± 11.0 | 130.9 ± 12.2 | 127.5 ± 11.0 | 130.6 ± 4.3 | 125.1 ± 9.6 | 121.4 ± 21.1 | 0.4391 |
| Activity | 129.6 ± 80.0 | 117.7 ± 51.1b | 68.8 ± 32.7a,b | 55.3 ± 23.1a,b | 142.0 ± 32.3 | 187.2 ± 39.6 | <0.0001 |
DBP, diastolic blood pressure; HR, heart rate; MBP, mean blood pressure; SBP, systolic blood pressure
CO2 data have been published previously.2
a
Value significantly different from that for isoflurane.
b
Value significantly different from that for pentobarbital–phenytoin.