Table 6.

Time (s; mean ± 1 SD) until peak cardiovascular values

	15% CO2	30% CO2	50% CO2	100% CO2	Isoflurane	Pentobarbital– phenytoin	P
HR	52.0 ± 48.1b	25.1 ± 20.3a,b	7.4 ± 6.8a	22.7 ± 25.8a,b	42.7 ± 43.0	21.2 ± 16.8	<0.0001
SBP	51.5 ± 21.4a,b	37.4 ± 22.5a,b	17.6 ± 6.7	17.5 ± 4.3	16.9 ± 7.2	19.8 ± 19.7	<0.0001
DBP	57.2 ± 27.5a,b	52.5 ± 20.6a,b	31.2 ± 13.8	23.1 ± 6.6	17.9 ± 6.0	11.8 ± 12.1	<0.0001
MBP	53.0 ± 24.1a,b	37.0 ± 23.3a,b	20.7 ± 9.4	17.2 ± 5.6	17.4 ± 6.5	17.7 ± 19.2	<0.0001

DBP, diastolic blood pressure; HR, heart rate; MBP, mean blood pressure; SBP, systolic blood pressure

CO₂ data have been published previously.²

^aSignificantly different from isoflurane.

^bSignificantly different from pentobarbital–phenytoin.