Table 8.

Amount of time (s; mean ± 1 SD) that mice were active during euthanasia

	15% CO2	30% CO2	50% CO2	100% CO2	Isoflurane	Pentobarbital–phenytoin	P
Activity time until ataxiaa	10.4 ± 10.2	6.8 ± 6.1	4.0 ± 3.6c	4.0 ± 2.2c	10.2 ± 2.1	13.0 ± 7.8	0.0006
Activity time until ataxia/s	0.14 ± 0.16b,c	0.14 ± 0.11b,c	0.13 ± 0.11b,c	0.17 ± 0.10c	0.34 ± 0.08	0.38 ± 0.18	<0.0001
Activity time until nose downa	12.7 ± 11.4c	10.9 ± 7.0c	6.9 ± 4.4b,c	4.7 ± 3.1b,c	15.7 ± 5.1	35.8 ± 10.6	<0.0001
Activity time until nose down/s	0.12 ± 0.11c	0.16 ± 0.11c	0.15 ± 0.09b,c	0.15 ± 0.09b,c	0.27 ± 0.09	0.37 ± 0.13	<0.0001

CO₂ data have been published previously.²

^aData were transformed for analysis.

^bValue significantly different from that for isoflurane.

^cValue significantly different from that for pentobarbital–phenytoin.