Table 1. Pairwise mean comparisons of percentages of MCM4, MCM7, and Ki-67 expression between esophageal histologic types.

	Comparison	Difference in percentage of expression
		MCM4	MCM7	Ki-67
Adenocarcinoma	High-grade dysplasia	−1.9	−2.2	−16.8
	Low-grade dysplasia	18.8 **	23.3 **	11.6 **
	Barrett's esophagus	33.7 **	40.2 **	16.2 **
	Columnar cell metaplasia	50.2 **	62 **	26.3 **
	Squamous epithelium	55.9 **	68.1	18.6
High-grade dysplasia	Low-grade dysplasia	20.6 **	25.5 **	16.8 **
	Barrett's esophagus	35.5 **	42.4 **	21.3 **
	Columnar cell metaplasia	52 **	64.2 **	26.3 **
	Squamous epithelium	57.8 **	70.4 **	23.7 **
Low-grade dysplasia	Barrett's esophagus	14.9 **	16.9 **	4.6
	Columnar cell metaplasia	31.4 **	38.7 **	9.5
	Squamous epithelium	37.1 **	44.9 **	7 **
Barrett's esophagus	Columnar cell metaplasia	16.5 **	21.8 **	4.9
	Squamous epithelium	22.2 **	28 **	2.4
Columnar cell metaplasia	Squamous epithelium	5.7	6.2	−2.5
Squamous cell carcinoma	Squamous epithelium	68.6 **	78.1 **	30.4 **

^**P < .05.