Table 2.

Multivariable analysis of predictors of disease-related and general quality of life in patients with inflammatory bowel diseases

	Coefficient	95% confidence interval
SIBDQ
Age > 60 years (vs. younger IBD)	2.34	0.82 – 3.87
Male gender (vs female)	2.33	1.38 – 3.27
UC (vs CD)	1.79	0.82 – 2.75
Active disease†	−12.11	−13.14 – −11.1
Ever steroid use	−1.80	−2.65 – −0.94
Ever anti-TNF use	−0.80	−1.40 – −0.21
Ever smoker	−2.10	−3.11 – −1.08
SF-12 PCS
Age > 60 years (vs. younger IBD)	−1.80	−3.21 – −0.38
Male gender (vs female)	1.45	0.59 – 2.32
UC (vs CD)	2.60	1.72 – 3.50
Active disease†	−8.49	−9.43 – −7.54
Ever steroid use	−2.20	−2.99 – −1.41
Ever anti-TNF use	−0.90	−1.45 – −0.35
Ever smoker	−1.48	−2.42 – −0.55
SF-12 MCS
Age > 60 years (vs. younger IBD)	3.78	2.26 – 5.30
Male	1.44	0.50 – 2.38
Active disease†	−6.09	−7.11 – −5.07
Ever steroid use	−0.94	−1.79 – −0.10
Ever smoker	−1.82	−2.84 – −0.81

^†Active disease was defined as an SCCAI > 2 in UC and HBI > 4 in CD

UC – ulcerative colitis; CD – Crohn’s disease; SIBDQ – short inflammatory bowel disease questionnaire; SF-12 short form health survey; PCS – physical composite scale score; MCS – mental composite scale score