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. Author manuscript; available in PMC: 2018 Jan 20.
Published in final edited form as: Circ Res. 2016 Nov 9;120(2):296–311. doi: 10.1161/CIRCRESAHA.116.309322

Figure 5. AdvSca1-SM cells exhibit multipotency potential.

Figure 5

AdvSca1-SM cells were isolated from SM22α-Cre-YFP mice by flow sorting, embedded in Matrigel™, and subcutaneously implanted into syngeneic WT mice. Matrigel™ plugs were harvested 14 days post-implantation for immunofluorescence analysis. (A). Representative stains of neovessels within plugs for YFP (green) and the SMC-specific marker, SMMHC (red). (B). Representative stains for YFP (green) and the macrophage-specific marker, F4/80 (red). (C). Representative stain of an endothelial cord for YFP (green) and the endothelial cell-specific marker, von Willebrand Factor (vWF)(red). Arrows = AdvSca1-SM-derived endothelial cells. Scale bars=50μm. N=4 independent analyses.