Figure 4. Dusp15 is necessary for Erk activity.
Quantitative RT-PCR was used to determine Ccl2, Vegfc and Pmp2 mRNA levels in (A) RT4 Schwann cells treated with siRNA against Dusp15 and (B) Dusp15-KO-RT4 Schwann cell line. (C) Ccl2 mRNA levels were measured in Dusp15-KO Schwann cells transfected with an expression plasmid for Dusp15 using quantitative RT-PCR. (*P<0.05)