Table 1.
Baseline characteristics
| Procaine benzylpenicillin and gentamicin (n=820) | Amoxicillin and gentamicin (n=816) | Procaine benzylpenicillin, gentamicin, and amoxicillin (n=817) | ||
|---|---|---|---|---|
| Age at enrolment (days) | ||||
| 0–6 | 361 (44%) | 360 (44%) | 362 (44%) | |
| 7–59 | 459 (56%) | 456 (56%) | 455 (56%) | |
| Sex | ||||
| Male | 465 (57%) | 419 (51%) | 425 (52%) | |
| Female | 355 (43%) | 397 (49%) | 392 (48%) | |
| Weight at enrolment (g) | ||||
| <2000 | 62 (8%) | 67 (8%) | 81 (10%) | |
| 2000–2499 | 145 (18%) | 144 (18%) | 128 (16%) | |
| ≥28 | 613 (75%) | 605 (74%) | 608 (74%) | |
| Weight-for-age (Z score) | ||||
| <–2 | 303 (37%) | 322 (39%) | 315 (39%) | |
| ≥–2 | 517 (63%) | 494 (61%) | 502 (61%) | |
| Number of signs present | ||||
| One | 720 (88%) | 717 (88%) | 704 (86%) | |
| More than one | 100 (12%) | 99 (12%) | 113 (14%) | |
| Fever | 330 (40%) | 337 (41%) | 348 (43%) | |
| In isolation | 296 (36%) | 303 (37%) | 306 (37%) | |
| Hypothermia | 71 (9%) | 71 (9%) | 91 (11%) | |
| In isolation | 43 (5%) | 46 (6%) | 55 (7%) | |
| Movement only when stimulated | 45 (5%) | 38 (5%) | 39 (5%) | |
| In isolation | 10 (1%) | 5 (1%) | 4 (<1%) | |
| Severe chest indrawing | 277 (34%) | 272 (33%) | 269 (33%) | |
| In isolation | 239 (29%) | 238 (29%) | 240 (29%) | |
| Poor feeding or suck | 210 (26%) | 205 (25%) | 191 (23%) | |
| In isolation | 132 (16%) | 125 (15%) | 99 (12%) | |
| Local infection | 122 (15%) | 110 (13%) | 126 (15%) | |
| Facility delivery* | 412 (50%) | 388 (48%) | 423 (52%) | |
| Maternal age (years)* | 25·9 (5·5) | 25·8 (5·7) | 25·9 (5·5) | |
| Maternal education (years)* | 0 (0–4) | 0 (0–5) | 0 (0–5) | |
Data are number of children (%), mean (SD), or median (IQR). Signs in isolation were the only clinical sign present at enrolment.
*
Data missing for place of delivery (n=1), maternal age (n=297), and maternal education (n=194).