1.
Summary of clinicopathological features of ICC, n (%)
| Characteristics | HLL | EHLL | NL |
| Gender | |||
| Female | 12 (57.1) | 8 (66.7) | 27 (38.0) |
| Male | 9 (42.9) | 4 (33.3) | 44 (62.0) |
| Age, years | |||
| ≤60 | 15 (71.4) | 6 (50.0) | 41 (57.7) |
| >60 | 6 (28.6) | 6 (50.0) | 30 (42.3) |
| Tumor number | |||
| Solitary | 12 (57.1) | 9 (75.0) | 41 (57.7) |
| Multiple | 9 (42.9) | 3 (25.0) | 30 (42.3) |
| Tumor diameter, cm | |||
| ≤5 | 6 (28.6) | 4 (33.3) | 40 (56.3) |
| >5 | 15 (71.4) | 8 (66.7) | 31 (43.7) |
| Hepatitis B | |||
| Negative | 11 (52.4) | 10 (83.3) | 38 (53.5%) |
| Positive | 10 (47.6) | 2 (16.7) | 33 (46.5) |
| Cirrhosis | |||
| Negative | 16 (76.2) | 12 (100.0) | 39 (54.9) |
| Positive | 5 (23.8) | 0 (0.0) | 32 (45.1) |
| Fer | |||
| Normal | 6 (28.6) | 6 (50.0) | 41 (57.7) |
| Higher | 15 (71.4) | 6 (50.0) | 30 (42.3) |
| CEA | |||
| Normal | 13 (61.9) | 8 (66.7) | 62 (87.3) |
| Higher | 8 (38.1) | 4 (33.3) | 9 (12.7) |
| CA19-9 | |||
| Normal | 5 (23.8) | 2 (16.7) | 48 (67.6) |
| Higher | 16 (76.2) | 10 (83.3) | 23 (32.4) |
| AFP | |||
| Normal | 20 (95.2) | 11 (91.7) | 50 (70.4) |
| Higher | 1 (4.8) | 1 (8.3) | 21 (29.6) |
| AJCC stage | |||
| I/II | 10 (47.6) | 9 (75.0) | 49 (69.0) |
| III/IVa/IVb | 11 (52.4) | 3 (25.0) | 22 (31.0) |
| Differentiation | |||
| Poor | 7 (33.3) | 7 (58.3) | 40 (56.3) |
| Well or moderate | 14 (66.7) | 5 (41.7) | 31 (43.7) |
| Vascular invasion | |||
| Negative | 13 (61.9) | 8 (66.7) | 48 (67.6) |
| Positive | 8 (38.1) | 4 (33.3) | 23 (32.4) |
| LNM | |||
| Negative | 15 (71.4) | 7 (58.3) | 71 (100.0) |
| Positive | 6 (28.6) | 5 (41.7) | 0 (0.0) |