Table 7.
Mean (SD) plasma regadenoson concentration-time profiles over 12 hours in the pharmacokinetic analysis set
| Time (minutes) | Regadenoson 100 µg Mean ng/mL (SD) |
Regadenoson 200 µg Mean ng/mL (SD) |
Regadenoson 400 µg Mean ng/mL (SD) |
|---|---|---|---|
| 0 | 0 (0) | 0 (0) | 0 (0) |
| 3 | 4.909 (1.177) | 9.048 (2.554) | 17.948 (6.205) |
| 9 | 2.001 (0.275) | 4.103 (0.627) | 8.567 (1.416) |
| 13 | 6.334 (1.249) | 10.486 (2.663) | 23.991 (5.493) |
| 19 | 3.132 (0.419) | 6.235 (1.033) | 13.370 (2.314) |
| 23 | 7.346 (1.199) | 13.005 (3.628) | 10.233 (2.192) |
| 29 | 3.928 (0.624) | 7.829 (1.295) | 7.284 (1.650) |
| 60 | 1.552 (0.342) | 3.478 (0.936) | 4.024 (1.370) |
| 120 | 0.936 (0.240) | 1.939 (0.376) | 2.455 (0.663) |
| 240 | 0.470 (0.124) | 0.956 (0.156) | 1.208 (0.302) |
| 480 | 0.076 (0.075) | 0.291 (0.096) | 0.364 (0.084) |
| 720 | 0 (0) | 0.078 (0.066) | 0.108 (0.070) |