| Several studies of microRNA, small non-protein coding RNA molecules, were conducted in blood and vitreous humor of AMD patients, but revealed few microRNAs consistently dysregulated in multiple studies. |
| Similar profiling studies were reported in mouse models of distinct AMD features and demonstrated some similarities with the human AMD findings, including miR-146a, miR-17, miR-125b, and miR-155. |
| Alteration of the levels of these miRNA in mice revealed an amelioration of the AMD-related damage, providing a promise for novel therapeutic approaches for this devastating blinding disease. |
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