Figure 4.

Curcumin treatment inhibited metastasis in vivo. A. Representative lungs from Female BALB/c-nu/nu nude mice are shown. B. Hematoxylin and eosin staining was performed on metastatic tumor and normal lung sections. Metastatic nodules are indicated by arrows at 200 × magnification. C. Metastases were quantified by counting the number of metastatic colonies in one histological section of the mid-portion of each lung sample from each mouse and determining the ratio of metastatic area to total area in histological sections from the mid-portion of each lung (n = 6 per group). A Student’s t-test was used to determine the statistical significance of differences between the groups.