Table 4.
C statistic | Change in C statistic** | P value** | |
---|---|---|---|
Overall | |||
Age, sex, race | 0.5749 | Reference | Reference |
+Risk factors* | 0.6983 | 0.1235 | <0.001 |
+Fasting glucose | 0.7438 | 0.1690 | <0.001 |
+hs-cTnT | 0.5838 | 0.0089 | <0.001 |
Fully adjusted without hs-cTnT | 0.7636 | 0.1888 | <0.001 |
Fully adjusted with hs-cTnT | 0.7644 | 0.1896 | 0.023† |
Low-risk groupa | |||
Age, sex, race | 0.5690 | Reference | Reference |
+Risk factors* | 0.6961 | 0.1271 | <0.001 |
+Fasting glucose | 0.7463 | 0.1774 | <0.001 |
+hs-cTnT | 0.5772 | 0.0083 | <0.001 |
Fully adjusted without hs-cTnT | 0.7658 | 0.1968 | <0.001 |
Fully adjusted with hs-cTnT | 0.7664 | 0.1975 | 0.040† |
Normal fasting glucose | |||
Age, sex, race | 0.5615 | Reference | Reference |
+Risk factors* | 0.6871 | 0.1256 | <0.001 |
+Fasting glucose | 0.7435 | 0.1820 | <0.001 |
+hs-cTnT | 0.5766 | 0.0151 | <0.001 |
Fully adjusted without hs-cTnT | 0.7258 | 0.1642 | <0.001 |
Fully adjusted with hs-cTnT | 0.7308 | 0.1693 | <0.001† |
*Models adjusted for: age, race-center, sex, total cholesterol, HDL-C, LDL-C, triglycerides, BMI, eGFR, systolic blood pressure, blood pressure–lowering medication use, smoking status, cholesterol-lowering medication use, family history of coronary heart disease, waist circumference, physical activity, education level, and annual family income level.
**Compared with age, sex, and race, except where noted.
†Compared with the fully adjusted model without hs-cTnT.
aDefined as no hypertension, hypercholesterolemia, or metabolic syndrome.