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Interruption of inhibitive effect of CD8+ regulatory T cells on memory CD4+ T cells by anti-Qa-1 and anti-CD8 antibodies. A. Qa-1 restricted CD8+ T cells were incubated with anti-CD8 mAb (25 µg/ml) and CFSE-labeled memory CD4+ T cells with Qa-1 mAb (10 µg/ml) (ratio of Qa-1 restricted CD8+ T cells to memory CD4+ T cells=4) for 96 hours. B. The proliferation effect was tested as previously described.
