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Bar graphs representing the nephrin, podocin and CD2AP mRNA levels in the kidney tissues among four groups. #P<0.05 vs. Normal; *P<0.05, **P<0.01 vs. DN model. All values are means ± SD (n=8). Real-time PCR demonstrated that nicousamide could significantly increase the mRNA levels of nephrin, podocin and CD2A in kidney tissues from diabetic rats compared to DN model.
