Figure 3.
miR-142 directly targets BACH2 in human GECs. A. Prediction of a miR-142 binding site in the 3’-UTR of BACH2 mRNA by TargetScan software (http://www.targetscan.org/vert_71/). B. HEK293T cells were transfected with indicated constructs and tested for luciferase activities. C. Western blot analysis of BACH2 protein in GECs transfected with C-miRNA or miR-142 mimic. *P < 0.05 vs. C-miRNA-transfected cells.