TABLE 2.

Packaging efficiencies of KUN replicon RNAs with different cell-adaptive mutations

Mutation	Packaging efficiency (PFu/ml) on day:
	2	4	6	8
Wt	5 × 106	1.3 × 108	1.8 × 108	3.3 × 108
NS2A/A30P	4 × 106	1 × 108	3.4 × 108	6 × 108
NS2A/N101D	4.4 × 104	1.3 × 107	4 × 107	NDa
NS5/P270S	1.0 × 105	6 × 107	1.3 × 108	ND
NS2A/A30P/N101D	1 × 104	1.1 × 105	1.2 × 106	9 × 106

^aND, not determined.