TABLE 1.
Summary of frequencies of cells which reactivated virus ex vivo and which harbored viral genome
| Mouse strain | Frequencya
|
|||
|---|---|---|---|---|
| Early (16 dpi)
|
Late (42 dpi)
|
|||
| Reactivating cells | Genome-positive cells | Reactivating cells | Genome-positive cells | |
| 129/SvJ | 1/2,086 | 1/207 | 1/6,194 | 1/695 |
| GzmA−/− | 1/2,090 | 1/219 | 1/5,036 | 1/720 |
| GzmB−/− | 1/868* | 1/166 | 1/5,884 | 1/572 |
| GzmAXB−/− | 1/280* | 1/100* | 1/7,405 | 1/835 |
| GzmB-cluster−/− | 1/201* | 1/67* | 1/1,777* | 1/406 |
| GzmAXB-cluster−/− | 1/153* | 1/30* | 1/1,263* | 1/233* |
| B6 | 1/621 | 1/227 | 1/9,051 | 1/709 |
| Caspase 3−/− | 1/125* | 1/30* | 1/14,250 | 1/1,121 |
a
*, statistically significant increase in frequency compared to response in wild-type mice.