Table 4.

Clinical pathologic correlations of select LC neuronal transcripts dysregulated in aMCI and AD

transcript	GCS	MMSE	Braak	NIA-Reagan	CERAD
cytc1	r = 0.64 (p < 0.0001)	r = 0.48 (p = 0.003)	r = −0.50 (p = 0.003)	r = −0.41 (p = 0.02)	r = −0.48 (p = 0.01)
nrf1	r = 0.57 (p = 0.0003)	r = 0.37 (p = 0.04)	r = −0.43 (p = 0.08)	r = −0.39 (p = 0.06)	r = −0.50 (p = 0.003)
gpx1	r = 0.54 (p = 0.008)	r = 0.44 (p = 0.008)	r = −0.42 (p = 0.02)	r = −0.42 (p = 0.01)	r = −0.39 (p = 0.02)
map1b	r = 0.59 (p = 0.0006)	r = 0.35 (p = 0.03)	r = −0.43 (p = 0.01)	r = −0.33 (p = 0.2)	r = −0.32 (p = 0.09)
nf-h	r = 0.54 (p = 0.0007)	r = 0.51 (p = 0.001)	r = −0.55 (p < 0.001)	r = −0.49 (p = 0.005)	r = −0.45 (p = 0.006)
ntn1	r = 0.52 (p = 0.0008)	r = 0.44 (p = 0.007)	r = −0.41 (p < 0.01)	r = −0.40 (p = 0.02)	r = −0.47 (p = 0.006)
synpo	r = 0.65 (p < 0.0001)	r = 0.52 (p < 0.001)	r = −0.58 (p < 0.001)	r = −0.47 (p = 0.008)	r = −0.45 (p = 0.005)
sod1	r = 0.22 (p = 0.1)	r = −0.11 (p = 0.5)	r = −0.18 (p = 0.6)	r = −0.09 (p = 0.6)	r = −0.28 (p = 0.1)