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. 2017 Jan 21;18:51. doi: 10.1186/s12859-017-1481-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Core methodology of RNA-TVcurve including four sub-block diagram: (1) RNA secondary structure prediction, (2) Characteristic representation for combining RNA sequence and secondary structure, (3) Construction of TV-Curve (Triple Vector Representation), (4) Wavelet decomposition of TV-Curves and multi-scale similarity measure based on TV-Curves