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. 2017 Jan 21;5:12. doi: 10.1186/s40560-017-0208-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Transendothelial resistance (TER) of HUVECs treated with septic serum. Normalized transendothelial electrical resistance (TER) was longitudinally measured in real time in human umbilical vein endothelial cells (HUVECs) with an electric cell-substrate impedance sensing (ECIS) device. HUVECs were then challenged with either septic serum before cytokine removal (bold line) or with serum from the same patient 24 h after cytokine removal (dotted line). TER normalization refers to the start point of the experiment for each condition (i.e., 5 min before septic serum incubation)