Table 2.
Cytokine, chemokine, and growth factor removal 24 h after Cytosorb® treatment
| Parameter | Pre | Post | Rel. reduction (%) |
|---|---|---|---|
| Cytokine removal (pg/mL) | |||
| IL-1a | 643.9 | 76 | −88.2 |
| IL-6 | 89.9 | 14.0 | −84.4 |
| CXCL8 (IL-8) | 68.4 | 19.9 | −70.9 |
| IL-9 | 12.9 | 7.2 | −44.2 |
| IL-10 | 80.7 | 40.0 | −49.6 |
| IL-13 | 7.1 | 10.8 | +51.5 |
| FGF | 48.1 | 21.4 | −55.6 |
| GM-CSF | 57.5 | 38.6 | −32.9 |
| CXCL10 (IP-10) | 24,723.7 | 2827.5 | −88.6 |
| CCL2 (MCP-1) | 375.0 | 45.9 | −87.8 |
| CCL4 (MIP-1b) | 125.4 | 39.2 | −68.8 |
| PDGF-bb | 719.8 | 245.3 | −65.9 |
| RANTES | 3912.2 | 1326.1 | −66.1 |
| TNF-a | 59.2 | 24.8 | −58.1 |
| VEGF | 63.7 | 19.5 | −69.5 |
IL interleukin, CXCL C-X-C motif chemokine, FGF fibroblast growth factor, GM-CSF granulocyte-macrophage colony-stimulating factor, IP interferon gamma produced protein, CCL C-C motif ligand, MIP macrophage inflammatory proteins, MCP monocyte chemotactic protein, PDGF platelet-derived growth factor, RANTES regulated on activation, normal T cell expressed and secreted, TNF tumor necrosis factor, VEGF vascular endothelial growth factor