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. 2017 Jan 21;17:28. doi: 10.1186/s12877-017-0423-6

Table 3.

Comparison of health-deficits across age categories among frail only participants defined using the frailty index

Variable 18–49 years
(n = 574)
50–64 years
(n = 254)
65+ years
(n = 125)
Chi-Square or ANOVA F-Test
P-value
Age 37.90 (1.04) 57.90 (0.42) 72.07 (0.26) <0.001
Sex (% male) 327 (57.0%) 135 (53.2%) 60 (47.7%) 0.399
Diabetes 101 (17.5%) 104 (41.1%) 56 (44.5%) <0.001
Thyroid problem 119 (20.7%) 53 (20.7%) 29 (23.5%) 0.841
Cancer 41 (7.2%) 61 (24.00%) 27 (21.3%) <0.001
Strokea - - - -
Heart diseasea - - - -
Arthritis 136 (23.8%) 150 (59.0%) 87 (69.4%) <0.001
Persistent cough 281 (48.9%) 85 (33.4%) 42 (33.3%) 0.010
Known kidney dysfunction 44 (7.7%) 23 (9.1%) 15 (12.3%) 0.442
Poor health 333 (58.00%) 143 (56.3%) 63 (50.1%) 0.581
Poor health compared to 1 year ago 320 (55.7%) 114 (44.8%) 46 (36.9%) 0.033
COPDa - - - -
Asthma 244 (42.6%) 62 (24.4%) 19 (15.4%) <0.001
Liver disease 51 (8.9%) 29 (11.0%) 10 (7.9%) 0.549
Trouble sleeping 459 (79.9%) 194 (76.3%) 85 (67.9%) 0.213
Resting HR (beats/min) 70.35 (1.17) 71.08 (1.25) 65.55 (0.66) <0.001
Systolic BP (mmHg) 114.53 (2.76) 120.11 (1.90) 125.97 (1.27) <0.001
Diastolic BP (mmHg) 74.52 (1.87) 73.42 (1.04) 68.48 (0.60) <0.001
eGFR (ml/min) 108.62 (2.31) 94.16 (1.30) 76.13 (2.15) <0.001
Albumin (g/L) 45.26 (0.83) 44.20 (0.35) 43.33 (0.29) <0.001
Haemoglobin (g/L) 142.82 (2.44) 142.02 (0.95) 135.73 (1.70) <0.001
Calcium (mmol/L) 2.44 (0.02) 2.43 (0.01) 2.42 (0.01) 0.023
Phosphate (mmol/L) 1.31 (0.03) 1.30 (0.02) 1.24 (0.01) <0.001
RBC count (10–12/L) 4.71 (0.13) 4.69 (0.08) 4.43 (0.05) <0.001
RBC distribution width (%) 13.33 (0.19) 13.27 (0.18) 13.54 (0.09) 0.043
Aspartate Aminotransferase (U/L) 37.09 (2.52) 34.68 (1.67) 30.47 (0.87) <0.001
HbA1C (%) 6.12% (0.15%) 6.6% (0.15%) 6.5% (0.08%) <0.001
Plasma glucose (mmol/L) 5.97 (0.32) 6.52 (0.25) 6.50 (0.19) 0.037

a n-value too low in the 18–49 category and could not report on numbers based on Canadian Health Measures ethics. Categorical variables are displayed as frequency (%) and continuous variables are shown as mean (standard deviation). Frailty was defined as having 3–5 of the Fried criteria. COPD chronic obstructive pulmonary disease, HR heart rate, BP blood pressure, eGFR estimated glomerular filtration rate, RBC red blood cell