Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 21;9:4. doi: 10.1186/s13195-016-0232-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Altered levels of sorting nexin-4 (SNX4) and β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in the brains of APP/PS1 mice. Immunohistochemistry was performed using anti-BACE1 (red) and anti-SNX4 (green) antibodies in wild-type and APP/PS1 mice aged 6 months and 24 months. The intensity of BACE1 and SNX4 in neurons is increased in the cortices of 6-month-old APP/PS1 mice compared with wild-type mice. The intensity of BACE1 and SNX4 in neurons is decreased in the cortices of 24-month-old APP/PS1 mice compared with wild-type mice. Scale bar = 20 μm