TABLE 2.
Insertion sites of IS6110 in Cameroon family M. tuberculosis strains
| IS6110 insertion sitea | Nucleotide no.b | Disrupted regionc | Gene name(s) or description | First descriptiond (source or reference) |
|---|---|---|---|---|
| CSIP-1 | 2265111 | Rv2017:Rv2018 | Unknown/unknown | This study |
| CSIP-2 | 2629008 | Rv2350 | plcB | 30 |
| CSIP-3 | 1522171 | Rv1355 | moeY | This study |
| CSIP-4 | 3790908 | Rv3377c | Cyclase | 22 |
| CSIP-5 | 3548751 | Rv3179 | ATP-GTP binding motif | This study |
| CSIP-6 | 2581467 | Rv2308:Rv2309c | Unknown/metV | This study |
| CSIP-7 | 3710391 | Rv3324c:Rv3327 | ipl site (IS1547) | 7 |
| CSIP-8 | 2364849 | Rv2104c:Rv2107 | Unknown/PE | 1 |
| CSIP-9 | 3493662 | Rv3128c | Unknown | 1 |
| CSIP-10 | 1989048 | Rv1758 | cutL cutinase | 22 |
| CSIP-11 | 1906551 | Rv1682 | Unknown | This study |
| CSIP-12 | 1880 | Rv0001:Rv0002 | dnaA/dnaN | 16 |
| CSIP-13 | 3746050 | Rv3347c | PPE55 | This study |
| CSIP-14 | 2784805 | Rv2476c | Transposase | This study |
| CSIP-15 | 3547517 | Rv3178:Rv3179 | Unknown/ATP-GTP binding motif | 1 |
a
Each IS6110 copy was named according to the band position in the LM-PCR pattern.
b
Insertion position of each IS6110 is according to the numbering of the M. tuberculosis H37Rv genome map (5).
c
The Rv number and the gene names are from the M. tuberculosis H37Rv genome map (5).
d
Reference of the first study to describe an IS6110 insertion in the same Rv.