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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Ann Behav Med. 2017 Feb;51(1):94–104. doi: 10.1007/s12160-016-9831-7

Table 4.

Relative risk of high allostatic load system parameters based on perceived long-term weight discrimination in the MIDUS study

Percent with
dysregulated
system		 RR 95 % CI p value
Cardiovascular 38.6
 Age and sex-adjusted 1.37 1.03, 1.81 0.03
 Model1a 1.26 0.92, 1.72 0.15
 Model 2b 1.20 0.89, 1.65 0.23
 Model 3c 1.24 0.89, 1.72 0.20
 Model 4d 1.23 0.89, 1.72 0.21
Metabolic 18.3
 Age and sex-adjusted 2.07 1.49, 2.88 <0.0001
 Model 1a 2.07 1.45, 2.97 <0.0001
 Model 2b 1.96 1.35, 2.82 0.0003
 Model 3c 1.66 1.07, 2.57 0.02
 Model 4d 1.56 1.02, 2.40 0.04
Glucose metabolism 23.5
 Age and sex-adjusted 2.29 1.62, 3.24 <0.0001
 Model 1a 2.29 1.43, 3.67 0.0006
 Model 2b 2.26 1.59, 3.22 <0.0001
 Model 3c 2.10 1.40, 3.15 0.0003
 Model 4d 1.99 1.34, 2.95 0.0006
Inflammation 26.6
 Age and sex-adjusted 1.89 1.37, 2.61 <0.0001
 Model 1a 1.99 1.44, 2.76 <0.0001
 Model 2b 1.91 1.37, 2.67 0.0001
 Model 3c 1.83 1.27, 2.64 0.001
 Model 4d 1.76 1.22, 2.54 0.003
Sympathetic nervous systeme 12.4
 Age and sex-adjusted 1.27 0.70, 2.32 0.43
 Model 1a 1.26 0.67, 2.35 0.47
 Model 2b 1.24 0.66, 2.32 0.50
 Model 3c 1.31 0.64, 2.68 0.46
 Model 4d 1.44 0.70, 2.96 0.32
Hypothalamic pituitary axis 43.6
 Age and sex-adjusted 0.94 0.71, 1.24 0.66
 Model 1a 0.96 0.71, 1.28 0.77
 Model 2b 0.97 0.72, 1.30 0.84
 Model 3c 0.94 0.69, 1.30 0.72
 Model 4d 0.95 0.69, 1.31 0.77
Parasympathetic nervous
 systeme 		19.6
 Age and sex-adjusted 1.42 0.90, 2.23 0.13
 Model 1a 1.42 0.86, 2.33 0.17
 Model 2b 1.38 0.83, 2.29 0.21
 Model 3c 1.28 0.75, 2.21 0.36
 Model 4d 1.29 0.75, 2.21 0.37

Long-term perceived weight discrimination represents the average value of perceived discrimination at baseline and at follow-up for those who had both measures. For individuals with only one measure, long-term discrimination represents their reported discrimination at that time point

a

Model 1 includes age, sex, race (white, black, other), household income (>$100,000/year), smoking status (never, former, current), educational attainment (< high school, high school graduate, some college, college graduate or more)

b

Model 2 includes covariates in model 1 plus engagement in regular exercise at least 20 min three times per week

c

Model 3 includes covariates in models 1–2 plus perceived race, sex, and age discrimination at baseline

d

Model 4 includes covariates in models 1–3 plus baseline BMI

e

Medication usage was not considered in the diagnosis of parasympathetic nervous system or sympathetic nervous system dysregulation