The main channels associated with afferent baroreceptor fibers are a mechanosensitive conductance (gm), a fast sodium conductance (gNa,F), 4-AP sensitive potassium conductances (gK,A and gK,D), a delayed rectifier conductance (gK,dr), linear leakage conductances (gNa,B and gCa,B), a sodium-potassium exchanger current (INa,K), a sodium-calcium exchanger (INa,Ca), and a calcium pump (ICa,P).